BEHAVIOR OF PAPILLARY LESIONS OF THE BREAST. A DECADE OF EXPERIENCE IN AN ONCOLOGIC CENTER

Abstract

Objective: To analyze the clinical, histopathological, imaging characteristics, and treatment of the papillary lesions of the breast treated at the Surgical Breast Departament at the Oncological Hospital Service of the Venezuelan Institute of Social Security from January 2010 to December 2022. Methods: retrospective, cross-sectional, descriptive, non-probabilistic study. Results: The average age was 55 ± 13 years, and the most common symptom is a palpable nodule (61.8%). 47.6% were classified as BIRADS 0 on mammography with an average size of 22.1 ± 16 mm, with the nodule being the most common finding (59.6%). In sonography, 38.3% were heterogeneous lesions, 51.7% had circumscribed margins, 50.6% were hypoechoic, with an average size of 21.1 ± 16 mm. The statistical agreement between the histological report in the core needle biopsy and its correlation with the final biopsy using the Kappa test was 0.055 (P = 0.098), demonstrating a poor correlation between the diagnostic method and the definitive histological result. The overestimation rate was 5.6% and the underestimation rate was 23.6%. Conclusion: Papillary breast lesions are uncommon, characterized by clinical, imaging, and histological heterogeneity. There is no clinical behavior, radiological findings, or histological features that can preoperatively predict the pathological characteristics of papillary breast lesions,

Key Words: papillary lesions, papilloma, papillary carcinoma, underestimation, overestimation, histological update.